PDCD1 Antibody / PD-1 / PD1 orb386225 from Biorbyt

Description

PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma

Product Specs
ItemPDCD1 Antibody / PD-1 / PD1
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb386225
Quantity20 µg, 100 µg
ApplicationsIHC-P
Conjugate/TagUnconjugated
PurityProtein A affinity chromatography
ReactivityHuman
TargetPDCD1
IsotypeRabbit IgG, kappa
ClonePDCD1/1410R
HostRabbit
Antibody TypeRecombinant
ImmunogenA partial length human protein was used as the immunogen for the recombinant PD1 antibody
NCBI Full Gene Nameprogrammed cell death 1
NCBI Gene AliasesCD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
ClonalityMonoclonal
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
StorageStore the recombinant PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide)

Specifications/Features

Application Notes: Titering of the recombinant PD1 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Application Dilutions: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

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